@zxc142: I have also started on Entyvio after being diagnosed with ICI (immune checkpoint inhibitor colitis) after 10 sessions of Keytruda. As my solitary lung lesion had resolved after 3 sessions my oncologist is hopeful the 10 infusions provided long term benefit as newer studies are showing one year max vs the previous two may be sufficient in such cases. I, too, will continue to be monitored with PET scans every three months. In the event of recurrence the option will either be chemo or gradual restart of Keytruda depending on how my colitis has responded to treatment. The risk of toxic side effects - which can increase with prolonged exposure to immunotherapy- can pose greater risk than benefit.

I, too, am curious about the necessity of lifelong Keytruda. From what I’ve been told, heard about in melanoma forums and read - such as https://oncodaily.com/oncolibrary/immune-oncology/lifelong-immunotherapy - there is no evidence for this and in fact can contribute to greater side effects
Does that correlate with your understanding?