I have used the 3 shots orthovisc for two years; I had a lymphatic reaction from the multiple needle injections with the 3 shot orthovisc......so.... I recently decided to go with the one shot monovisc. Monovisc and Orthovisc have reacted similarly in terms of knee symptoms. THey are as per my understanding bioidentical to my bodies' hyaluronic acid and only differ in the way the hyaluronic is formatted to lay and in that only one shot is needed for the monovisc. The side effect record is also good for both of them.
My doctor did use a small small amount of cortisone in the monovisc shot because of my previous lymphatic reaction with swelling etc. due to the needle impact in the knee.
I have noticed that there does seem to be a period of time needed for both gels to settle in with some catches and sounds. All this evens out for me within about a week.
I also use cartigenix hp for inflammation. I am not sure about this product, but am willing to try it to see how it helps or not.
I also use SPM to help resolve inflammation; this was prescribed by my neurologist.
I also use a "uploader" or "off loader" brace on my knee to keep the "grinding" on what is left of my cartilage down as much as possible.