← Return to Rituximab or Remicade for Rheumatoid Arthritis RA

Discussion
Alta Net avatar

Rituximab or Remicade for Rheumatoid Arthritis RA

Autoimmune Diseases | Last Active: Apr 24 11:50am | Replies (28)

Comment receiving replies
Profile picture for pm56 @pm56

I’ve done both. Rituxan I had the two loading doses and then the follow up dose, but I subsequently developed a bad case of Covid so my doctor took me off Rituxan, and I was still on a fairly high dose of Medrol and hadn’t had a chance to taper, so I never got a chance to find out if it worked or not. It is a B cell depleting therapy and I tolerated it well without any severe side effects other than being a bit tired on infusion day.

I trialed 6 other biologic drugs without success after that and Remicade was going to be a last resort for me last summer as the dose can be increased and if you need more suppression, your doctor has the option to shorten the time between infusions so instead of every eight, you can get them every six or even every 4 weeks so there’s a lot of flexibility. Unfortunately for me, after the second loading dose I developed ataxia so they stopped as there was a concern that I might be at risk of MS. It can happen in a very, very tiny percentage of people, but I already had tremors and hyper reflexia so I already have some CNS issues so the decision was made to stop the Remicade just in case. But it didn’t cause any GI issues or cause any headaches or anything. My doctor said for many it works very well because it is one of the very few drugs that gives a doctor the ability the tweak the dose and change the intervals to fine tune the amount of suppression a patient needs. I hope it works for you 😊

Jump to this post


Replies to "I’ve done both. Rituxan I had the two loading doses and then the follow up dose,..."

@pm56

Thank you for sharing. Rituximab in addition to RA is now considered for other autoimmune conditions, like scleroderma. This may be my next treatment, as I have arthritis related to scleroderma. Hoping that it may work for me.

Remicade sounds like a much stronger medication with potential for neurotoxicity. May need to be careful with it. Thanks again for your insights.