Creon is made from porcine (pig) pancreas, which means the enzymes are very similar to the ones the human pancreas naturally produces. That’s why it works so well for EPI — it’s essentially replacing what your body is missing.

Products like Vital Digest use plant or microbial enzymes, which can help with general digestion, but they are not identical to human pancreatic enzymes and may not work as effectively for EPI.

So even though both contain enzymes, they are not the same in how closely they match natural pancreatic function.

EPI stands for Exocrine Pancreatic Insufficiency.