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← Return to bone pain four months after Reclast Infusion
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bone pain four months after Reclast Infusion
Osteoporosis & Bone Health | Last Active: 21 hours ago | Replies (99)Comment receiving replies
@dannyandebbie, hi.
PMR is a generalized inflammatory disorder with the over production of IL 6 a protein in the immune system. It causes widespread inflammation felt in areas of high density of bursae ( hips and shoulders) and synovial tissue (joints) and areas of previous damage.
I was looking for an article that mentioned bisphosphonates not causing autoimmune systems, but reactivating dormant or exciting pre-existing systems. It seems to me that individuals with autoimmune disease are more likely to have this terrible reaction to zoledronate.
TNF inhibitors block the cytokine cascade and can slow the degeneration of discs.
I can see why you would never trust another injection.
https://www.arthritis.org/diseases/polymyalgia-rheumatica
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@gently from what I see, a dose of prednisone would be an indicator if one has PMR….meaning, if prednisone treated the symptoms then it could be PMR, correct? I had prednisone therapy and it did nothing for my symptoms; symptoms that did develop after the Reclast infusion. Again, underlying conditions probably could have added to my issues, triggering these symptoms. Guess I’ll never really know as my endocrinologist sends me to rheumatologist who sends me to neurologist who suggested I see an endocrinologist. I see an endless circle that would make others wealthy and myself frustrated, so, I chose to just step out of that circle and go day by day and a little help from my physical therapist who I go to biweekly, for now!