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← Return to bone pain four months after Reclast Infusion
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bone pain four months after Reclast Infusion
Osteoporosis & Bone Health | Last Active: 21 hours ago | Replies (99)Comment receiving replies
kabmax259,
"While the patient's symptoms, including weakness and tenderness in the upper extremities, initially resembled those of PMR, several factors argue against a diagnosis of PMR in this case. Firstly, the temporal relationship between symptom onset and zoledronic acid infusion raises the possibility of an adverse drug reaction rather than an underlying PMR. " https://pmc.ncbi.nlm.nih.gov/articles/PMC10404464/.
Reclast stays in your bone for ten years or so. Your inflammatory reaction may subside in response to the prednisone because the cytokine response is self sustaining and no longer triggered by the initial flood of zoledronic acid.
There are far more patient reports of this than medical journal reports. I hope the pain goes away.
Replies to "kabmax259, "While the patient's symptoms, including weakness and tenderness in the upper extremities, initially resembled those..."
@gently
Thank you for your informative response. I wish I would have known more before I had Reclast infusion. I also had cancer last year and was having Nivolumab immunotherapy infusion. After 4 months of that, I started noticing a reaction in my body (but milder than after Reclast.) I stopped the immunotherapy but 2 months later had the Reclast infusion. There is one Dr. that thought the Nivolumab caused a adrenal insufficiency or set-up the inflammatory process for the Reclast. I just don't know how to proceed with my new Rheumatologist, who I meet via telemed tomorrow. In the .gov link you sent, it mentions tests to rule out PMR. Also, my Primary said Reclast stays in system for one year. Can I find information stating 10 years? Thank you again.
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@gently can I inquire, what is PMR? I was told the same about this medication remaining in your system for years! It has been 21 months for me. Yes the symptoms seem to vary as well as bother different areas of one’s body. I had a lot of harsh symptoms, shoulders, left foot, nausea, flu like symptoms and blurred vision. Some of the symptoms have decreased in intensity yet still remain. I did the prednisone taper medication and really did not seem to do anything. I do know that I’ll never receive another infusion of any kind. It does affect people differently. Not sure if one’s health and prior medical issues play a part; wish there were a lot more studies to better provide to patients because I had none of these symptoms prior. However, I have had Ankolosing spondylitis for some 50 + years and bladder cancer 5x in the last 16 years; not sure if this played a part in my continued symptoms from the Reclast. I am a male, 69 years old, 5’2” about 119 lbs. they say I have degenerative disc disease in my lower back…of course, handling logs for the past 45+ years evidently played no part; I guess. Just Remember! We are our own advocates! Review treatments and medications before agreeing! Best of luck!