← Return to Cancer in Prostate and Seminal Vesicles: Prostatectomy or SBRTw/ADT?

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Profile picture for northoftheborder @northoftheborder

"Prostatectomy or SBRTw/ADT?"

The answer is yes. 🙂

It's actually pretty amazing that we have multiple excellent and pretty-much equally-effective options (there's also Tulsa Pro). There are differences in possible side-effects, but you don't find out which (if any) side-effects you'll end up with until weeks, months, or even years later, so in a sense, it's out of your control either way.

The statistical comparisons you'll see are largely splitting hairs, especially when they're comparing numbers from different studies with different methodologies, which makes the margins of error swamp any claimed "advantage" of one over the other. The only things worth paying attention to are head-to-head clinical trials that applied the same controls to all participants, but they're relatively rare.

The websites that try to extrapolate from those for things that weren't specifically investigated — e.g. if you're 67, have South Asian ancestry, and your cancer is Gleason 3+4 with no BRCA mutations, treatment X is 15% more effective than treatment Y — are are statistically questionable.

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Replies to ""Prostatectomy or SBRTw/ADT?" The answer is yes. 🙂 It's actually pretty amazing that we have multiple..."

@northoftheborder So true, North, and these retrospective studies that look at 350,000 men treated over a 20 yr period with Gleason scores of X or Y, come to conclusions that have zero regard for contributing factors such as Decipher, Surgical path findings, etc…
You really have to wonder at the ‘scientific’ nature of these…
Phil