I've had two infusions and will have third and final one this summer. I've had no side effects. My dexa scan this past summer showed improvement in spine and small improvement in femur. My only regret is that I wasn't aware of Evenity or Prolia before I started Reclast and my endocrinologist at that time never explained the options. My understanding is that the first two are bone building and the last, Reclast, is bone maintenance. I now have a new endo and we're taking it from where I am. I understand that I'll be taking a "drug holiday" after this last infusion, and I don't know where we'll go from here. I'm active, strength train, take calcium, D3 with K and MK7 daily.