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Should I add ADT to Salvage Radiation at age 76?
Prostate Cancer | Last Active: Mar 26 6:43pm | Replies (30)Comment receiving replies
@jeffmarc Just saw a post on the Inspire forum where a patient with Gleason 4+5 and Decipher 0.98 consulted with Dr. Kishan who was involved in the POSEIDON study the ASCO recommendations about ADT were based on. Dr. Kishan noted that the POSEIDON study pertained to a general post-surgery population (i.e., all Gleason scores), whereas high Gleason scores are important in the decision making for the use of ADT. Also, for that study, men's Decipher scores were unknown and/or not used although high Decipher scores should be considered as well on the need for ADT with salvage radiation. See the complete post here,
https://www.inspire.com/groups/zero-prostate-cancer/discussion/bda128-adt-and-salvage-radiation-after-surgery/
Replies to "@jeffmarc Just saw a post on the Inspire forum where a patient with Gleason 4+5 and..."
@wwsmith
It seems the complete Post is actually here
https://www.urotoday.com/video-lectures/asco-gu-2026/video/5413-poseidon-meta-analysis-re-examines-the-role-of-adt-with-salvage-radiation-for-prostate-cancer-amar-kishan.html
In this particular case, the PSA went from .3 to .7 in 18 months. That’s not a very fast, doubling rate. The article does say ADT over .5 for a short term does make sense. I know in my case I only had .2 and I got A six month ADT shot. I didn’t even notice the side effects back then, But it reoccurred in 2 1/2 years And I had to go back on ADT full-time.
When the doubling rate is so slow, they might even consider not doing the ADT. I would let a doctor make that decision.
Interesting article though.
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@wwsmith
Thanks so much for your input case and attaching this link < 3