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Statins that won't cause/worsen neuropathy

Neuropathy | Last Active: 7 hours ago | Replies (27)

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I went off of rosuvastatin (20 mg) after reading that study, too. I developed severe small fiber neuropathy in 2024 in hands and arms, then feet and legs. I went off of the statin and at the same time started R-ALA (600 mg, daily). My symptoms improved about 2 months later, but I am a skeptic about the rosuvastatin being the cause. My cholesterol again bounced up when checked 6 months later. Mine is genetic because I eat a plant based diet with plenty of fiber and almost no processed foods. Anyway, Zetia (generic ezetimibe), a non statin, brought it down quite a bit. With my family's history though, I need to bring my LDL down even further, so after much research, I decided to combine Zetia with a very low dose of rosuvastatin (5mg. every other day). I think that the study that you mentioned was in PUBMED and Lancet has been disputed. There really are not enough good studies. I am monitoring my symptoms, but think that this combination should be a lot less likely to worsen neuropathy. The inhibitors would be my first choice; however, I am tired of fighting insurance to pay for it. This trial of the combo will help me determine whether I need the inhibitors (much more costly). I had no side effects on Zetia after the second week and it lowered my LDL from 149 to 115. Good luck with whatever you decide.

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Replies to "I went off of rosuvastatin (20 mg) after reading that study, too. I developed severe small..."

@jankavs
Wow. Am in your situation. Familial. Levels way too high as is calcium score.
Cannot go off Crestor Zetia and probably Repatha soon
Sucks.
So using RALA . Benfotianine
B12
Excercise etc
Anything else I could do?
Best of health to you.
Feel free to message

@jankavs
Hello,
I have family related hi cholesterol too & was just diagnosed w/ myasthenia gravis. I am on simvastatin & Ezetimibe. I cannot get a straight answer from either my primary dr or neurologist whether to stop the statin & only tk Ezetimibe...my neuro NP said Ezetimibe does not work by itself to control cholesterol. Did you say you took Ezetimibe w/o a statin & if so, how did it work for you?
Im so 😕 confused