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Straight off the internet -
"Kevzara (sarilumab) works by blocking interleukin-6 (IL-6), a protein that drives inflammation, to reduce joint pain, stiffness, and systemic inflammation in conditions like rheumatoid arthritis and polymyalgia rheumatica." This drug is FDA approved for PMR.

I am on Tyenne, a bio-similar drug to Actemra, this drug also is an IL-6 blocker. I am being treated for Giant Cell Vasculitis and it is approved for GCA. I most likely have PMR as well. Regardless, the Tyenne injections have reduced the pain, in about 10 weeks, to a very low level. I have had the pain since 2019 and have been on and off prednisone multiple times since then.

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Replies to "Straight off the internet - "Kevzara (sarilumab) works by blocking interleukin-6 (IL-6), a protein that drives..."

@jabrown0407
Hi. I just had my first infusion of Tyenne on march 17. For GCA vasculitis in the aorta . It went well. Next infusion April 17. I am hopefully it goes as planned. Currently on 21 mg prednisone, tapering again after next infusion. Have been on prednisone for three years. Ugh. Hopefully your treatment is progressing nicely.