@e74
I was on Rituxan for several years very successfully. However I then went into a one year phase where my autoimmune system was so depressed i was constantly sick with one infection after another. I was prescribed antibiotics 10 times that year because they had to treat the infections. When my Dr switched me to Simponi I did much better for a while. I have now been on Orencia very successfully for about 5 years.