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Yes, as I got down to the lower doses of prednisone the cramps started to go away. I’ve been off prednisone now 3 wks, I haven’t had any cramps at all since then. The K2 didn’t stop all the cramps but definitely helped when I was on higher doses of prednisone—I even had cramps of my fingers. The study I referenced talked about 180 mcg daily, but the pills I got off Amazon ( Now brand, MK-7, Vit K) were 100mcg, so I took one twice daily. Hope this helps.

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Replies to "Yes, as I got down to the lower doses of prednisone the cramps started to go..."

@provdam
Glad to find this discussion which confirms my somewhat severe leg and hand cramps (fingers & toes would freeze in strange positions) while on high doses of Prednisone for GCA/PMR. Calf cramps sent me through the roof! Can't remember when my night soaking-sweats stopped--thinking not too far into Prednisone treatment & getting Tyenne onboard to start the slow Prednisone weaning. I didn't do much about the cramps but eat more bananas (didn't know about avocados, but do eat them). Have been off Prednisone since July 2025 and now on monthly Tyenne infusions with no adverse symptoms perceived & labs so far so good.