Looking for cases of people using a second anabolic after the first

I had MRI (showed weakend cortices and thinner after tymlos / weakend microarcheture also) and traditional CT on the feet- CT repeated one year after to assess diffrences. CT Imaging gave little info. I was told that a 'quatitative CT' would have bene better to do since it can measure the width of the cortices. I do not know if that is true - or where one can arrange a 'quantitative ct'.
Therefore my progress is based on personal symptom evaluation.; distance I can walk without needing to sit - how long I can stand ( more then 3 mins etc ) . It is also based on how 'crunchy' my feet feel - I realize that is not scientific but I can feel bones fatigue - thats my danger zone. I remain in heavily supportive footwear to reduce flex of feet bones. I have not fractured for 2 years.
Feet do not ache. They are alwasy better after rest . My Excereice is primarily lying floor work since I cannot stand for very long. I am Walking to one mile now which is a God send. I started at 25 ft.
I use a low intensity vibration platform to provide additional stimuation to bones; this took along time to acclimate to, due to nerve trauma becasue of the fractures. I didnt know that was a thing but my bones were so flet that they were compressing - like some people expereince in the spine- lA wodnerful DO helped me with thru that and the nerves settled down., thankfully Evenity has helaped me gain back some strenght in the feet , I am very thabkful, I have a Dexa soon and will chekc the other areas but honestly its my feet that Im concerned with. ( before med; Spine was -3.9 / hip -4/ forearm -4.7 / after tymplos spine -2.6 / hip -3.6 / forearm - 4.7)
WHere ever youare on your path I send postive prayers for your restoredhealing and strnght. This platform is very helpful and I am appriciative for the community support.

cat1203, teriparatide and romosozumab work through entirely different mechanisms. Evenity may well work for you if Forteo hasn't.
I responded to suggest that you use bone markers to determine if the medication is effective, so that you don't spend a year on Evenity either uselessly or worrying. Having a serum P1NP before Evenity and a month in would let you know. Some like the second P1NP two months in but I'd be insistent not wanting a second injection without knowing. The jump in P1NP will be dramatic, even after successful use of Forteo.
Even further from your question (sorry), I think of Forteo, when is doesn't work,as a valuable hint that you may have secondary cause for osteoporosis which should be resolved before resuming medication, the main concern would be hyperparathyroidism.
I wonder from your post if you had some, but not enough gain from Forteo. I'd have quit Forteo after the first dexa if I didn't have bone markers telling me that this drug was doing some heavy lifting. Even after the second dexa when the only remarkable change was a change in fracture risk, I may have quit.
Forteo does something that Evenity can't. It rebuilds the cartilage structure in trabecular bone lost in the breakdown of bone. Cartilage isn't evidenced on dexa. I reasoned that Forteo is busy rebuilding cartilage, because I'd lost a whole lot before starting medication. I'm on extended Forteo.
You are on unchallengeable ground asking for bone markers after (wasting) 17 months without evidence of gain
I suspect you'll have good results on Evenity in no small part because of prior Forteo use.

@dmshope

Please let us know your results. I had very good gains with Evenity and hop you do too. What is the treatment plan that you and your doc have decided on post Evenity? What dug will you follow it with?

@cat1203

Your statement that you hope that your new rheum, who you cannot see until late May, uses bone markers.....raises an important issue that perhaps people here on Connect have found a way to respond.

Is there a way to find out whether a potential medical practitioner is open to and/or using blood markers before you go through the trouble AND the wait for an appointment?

I am looking for a bone specialist at present but I want to know ahead of any appointment that that provider is open to the use of bone markers. Not interested in wasting my time or theirs....was able to convince a previous primary care doctor to order CTX and (less often) P1NP. The cost of these tests is covered by my Medicare if there is a physician order.

Leeosteo,
Three years ago the endocrinologist was insistent that I would have two years of Forteo followed by two years of Reclast.
I knew I was safe for two years, accepted the prescription, and began to search for a replacement endocrinologist willing to prescribe continued Forteo. i didn't object to Reclast openly, but I wasn't going to take it.
I found a doctor, plus I realized that I can get this medication in other countries.
Suddenly, unexpectedly, without discussion in what would have been our last appointment the doctor said, "I think you should stay on Forteo." When I asked how long he said, "until your T score is -1."
Imagine.
I don't know why he changed his mind. There is chatter out there, mostly on (the inaccessible to patients) Echo about determining which osteoporosis patients would benefit from extended Forteo.
The dexa evidence of the medication working isn't showing on my dexa. But my bone markers couldn't be more perfect.
I'm so convinced by the mechanism of action of these pth medications that I don't want to slow down the cells that carry away damaged bone. I want renewal. I want the architecture of lost bone restored. If I fracture, along the way I'll have a different song to sing.
I was intended to have the three year dexa in March, but delayed till September. The March bone markers are again, perfect.
I'd like to see a clinical trial or hear from even one person who took Forteo for 18 or 24 months, and followed with Evenity for three months ( the time of greatest gain for Evenity) and then resumed Forteo. But I don't want to do it.
I'm assuming you haven't done bone markers. It would be interesting to have them now. Usually, at 17 or 18 months the CTX (representing the work of the osteoclasts) has become more dominant than the osteoblasts.
And signals the need for a break from Forteo.
So happy to hear from you again, leeosteo and with such good news about getting away from Alvogen's product, and, especially, your success with Forteo.
Either Reclast or Evenity (barring side effects) should give you good results. I'd want to know the doctor's after Evenity intentions.
Bless your bones.

Hi. I
ve been on 2 years of Tymlosfollowed by 1 year of Evenity (last injection 3/18/26. The Dexa Scan I had three dats ago showed little improvement over these three years!! I am so very disappointed.
I have to do something in the next few weeks and also haye to lock in bad results, but my Dr. said she doesn't know why I've been resistent to making bone gains. My blood work looks good.; parathyroid, kidney functions. My Hashimotos is managed with Levothyroxine. Not sure what to do next. My Dr. wants me to do the Reclast infusion to lock in what tiny gains have been made on some scores. My L-2 decreased from -2.8 (2025) to -4.0 (2026).!! I really would like to know why I'm not making gains. Anyone have similar news to share and possible next steps?
thank you