← Return to Slight rise in PSA 24 years after radical prostatectomy!

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@melvinw Thank you for sharing your experience with the salvage radiation. I'm sure things have changed a lot in 20+ years. While I believe in 2nd and 3rd opinions, I'm just wondering if the opinions from other oncologists you saw were very different from each other. Best wishes to you! Mike

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Replies to "@melvinw Thank you for sharing your experience with the salvage radiation. I'm sure things have changed..."

@domiha The first RO I met with wanted to add short term ADT (Orgovyx) to RT. Next I talked to an MO who wanted to hit me with all kind of hormone therapy drugs along with RT. Then I met with another RO. She was more agnostic about the ADT and was totally comfortable with just treating with radiation.

Because I was intermediate risk, along with low PSA and a long time to recurrence, adding ADT to RT was big gray area. Because of the potential metabolic risks of ADT, some docs won’t recommend it for intermediate risk relapse patients with PSA less than 0.5.

The first RO hit me with a FOMO argument for doing ADT which I didn’t appreciate. He also cited a published trial in support of his ADT recommendation. I thoroughly perused the paper he cited and challenged him on how he was extrapolating the results of the study to apply them to me. I got him to admit the he was overreaching the data. The MO just reflexively recommended a battery of hormone therapy drugs without any discussion of risks and benefits. When I pushed back, he said “okay” and passed me on to the RO I finally worked with. She also was more tuned into my goals and priorities, and comfortable with my assessment of the medical literature.