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Advice on Exemestane

Breast Cancer | Last Active: Apr 7 1:52pm | Replies (48)

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I was started on Anastrazole. I had short episodes initially (headaches, nausea, dizziness) that would go away in a couple weeks. Pain started at about 3 months on the meds. Generalized hip and lower back aches which I could deal with but then the sharp stabbing pain that would move round - left ankle, right hip etc - to the point where even meds didn’t help and some days it was non-weight bearing. At 9 months, he said “you shouldn’t have to live in pain” and stopped for a month before starting exemestane. I take it in the evening because the instructions are to take after a meal. Not always hungry at breakfast so this is the only meal I eat on a regular basis. (Mention this because I see some take it at bedtime - is this empty stomach or taken with a snack?) anyway, still the lower back discomfort but no major pain. My main side effects are extreme fatigue that started about month 4 followed by insomnia 3 months later. I also feel weaker than I think I should - could be related to the fatigue - but I just can’t do what I used to be able to do. Currently I’m lucky to get 4 hours a night. Magnesium helped for a couple weeks but then not much. He did a 1 month medication vacation late last year and things started to improve but worsened again after I went back on. So far, the only thing offered I to stop this one and try letrozol but that seems to be the worst of the lot so declined for now. And yes, my hair is thinning on this medication.

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Replies to "I was started on Anastrazole. I had short episodes initially (headaches, nausea, dizziness) that would go..."

@mistymar
Hi
I take the Exemestane at lunch time with lunch. I sit down and eat then take the pill. I am tired at night and sleep. I decided that having some symptoms for half a waking day might be better, for sleep and other side effects. Just new at this drug, so far so good. A little more tired but, a lot of that is weather related as it is spring here, or trying to be spring! Also, the pill. Having a real struggle with taking HERCEPTIN though, I don't have Metastatic breast cancer. Had mastectomy and chemo. 74 and not sure about this every 3 weeks for a year?? Anyone have any rate of success with this? Any advice from monitor or patients.
To help me decide, of course, it's my decision just really confused about this right now. any facts would be greatly appreciated, and knowledge is power!!