Both Anastrozole (1st trial) and Letrozole (#2) initially stared out fine with me, no side effects.
However, 3 months into both my headaches were severe at times. I am a migraine sufferer. Sometimes the headache was migraine-like (throbbing right temple) or more scary was an overall pressure in my head or forehead that felt like I was going to have a stroke. Tylenol ES 1000 mg. daily was just about a constant, along with ice packs on my head - day time or night time going to bed.
Off Letrozole for 7 days now, headaches have improved but can still occur, not as severely.
Seeing my breast oncologist today. Expecting Exemestane now. I am 10 months into the AIs so I have a very long road ahead of me. Hoping the headaches will not be a major problem on Exemestane.
But as we all know...nothing is a given on our journey! The very best to all!