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My husband went from T2 with 4+3 unfavorable to 4+5 , T3a after they examined the whole gland. He had "iffy" margin on one tiny spot where 3+3 was present and unifocal EPE that had negative margin but it pushed him into T3a category.
His tumor burden was very small, I forgot the %, but it was really one single small spot with cribriform and IDC. His post op uPSA was 0.014 and all looked promising but now 7 mos post op his uPSA rose to 0.026 . It is still early to know what is going on but I am not holding my breath : (.

Unfortunately with cribriform and IDC there is no telling what is in the future. Those are very aggressive features and one has to be extra vigilant with follow-ups . We do uPSA every month. Cribriform and IDC can cause shorter progression free periods BUT everybody is different and I am sure that there are patients with all those bad findings who have 10 or more BCR free years in spite of it all , and I am wishing you with all my heart to be one of those < 3.

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Replies to "My husband went from T2 with 4+3 unfavorable to 4+5 , T3a after they examined the..."

@surftohealth88 Thanks for the note and well wishes. I'm going to be aggressive in my vigilance. Like for like. Rooting for you and your husband. We'll get there, even if we have to take the scenic route. Game on.