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Everything quit working

Prostate Cancer | Last Active: Mar 20 12:24pm | Replies (24)

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Profile picture for jeff Marchi @jeffmarc

You are in the position. I am worried about happening to me. Since I have BRCA2, I have a drug called a PARP Inhibitor that works for those that have the genetic problem of BRCA. The next step if that doesn’t work for Long is Pluvicto. It is supposed to be very effective for those that have BRCA.

Have you had genetic testing? There is both hereditary and somatic, genetic test testing. You may not have something in your hereditary, but you could have something that came up when your cancer cells Had a genetic change. I know people who have had their cells become BRCA2. You definitely want to run those tests.

Be aware that it works really well for 33% of people OK for 33% of people and not at all for 33% of people.
If you have certain genetic issues, either hereditary or somatic, it can affect how well Pluvicto Works. You can ask for a somatic test before doing Pluvicto To find out if you’ve got Genetic changes Due to the cancer.

If you have BRCA2 or ATM It seems to work better. If you have RB1, PTEN or TP53 They are Pluvicto resistant.

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Replies to "You are in the position. I am worried about happening to me. Since I have BRCA2,..."

@jeffmarc Yes, I had those tests and was told everything is OK

@jeffmarc Hey Jeff, You may have posted this one or more times, but I don't recall how long you have been diagnosed, and therefore how long you have been a survivor after your RP and/or radiation therapy. How many months or years are you into your journey?