The short answer is yes. The rather long story is as follows: I'm a retired ER doc, age 76. I've been quite active physically most of my life, primarily with martial arts, but also with skiing, golf tennis, etc. I've accumulated a lot of joint injuries and pain, primarily shoulders and knees. About a year ago my pains began to get worse, and even my hips, ankles, and wrists variably became painful. Eventually I gave up and saw my primary MD, who did an autoimmune panel and referred me to Rheumatology. The labs were mostly normal, except for mild anemia, elevated platelets, and moderately elevated CRP. I saw a rheumatologist who said she didn't see anything rheumatologic., but after a few wks, with the help of some physician friends, I became convinced that I had PMR. Eventually I sent an email to the rheumatologist and my primarly explaining why, and she agreed to do a prednisone trial. On 20mg I felt better within hours, quite good within days. I stayed on 20mg for a month, then tapered 2 1/2mg every 2 wks until 10mg, then 1mg every 2 wks until finished. I've now been off prednisone for 2 weeks, just repeated my labs and they are normal. My knee pains never quite went away and now have come back to almost pre-PMR level, but that is probably my osteoarthritis, not PMR. I know I've had an easier time getting off prednisone than most, but hopefully it will give some of you some reassurance that it is possible.