Replies to @shmbrd Have you considered taking an oral form of a bisphosphonate instead of an infusion? At...

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Osteoporosis & Bone Health | Last Active: Mar 29 6:28am | Replies (77)

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@daisy17

@shmbrd Have you considered taking an oral form of a bisphosphonate instead of an infusion? At least then you would be getting a lower dose and could stop the drug if you have side effects.

I don't mean to provide medical advice but check into the "absolute risk" and benefit ratio of bisphosphonates. Several studies show they may improve DEXA scores but offer minimal benefits on fracture prevention. Doctors disagree but that's what I've read. https://www.ncbi.nlm.nih.gov/books/NBK598429/

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Replies to "@shmbrd Have you considered taking an oral form of a bisphosphonate instead of an infusion? At..."

kfhoz | @kfhoz | Mar 15 11:09am

Below is a more recent paper (2023) than the one from 2011 that @daisy17 linked. There is lots of active research in osteoporosis and the 2023 paper also supports her comments. It has great discussions and a table of relative risk (RR) vs absolute risk reduction (ARR).
https://www.amjmed.com/article/S0002-9343(24)00101-3/fulltext.
Excerpt: "... For patients at high risk of fracture, especially those with prior fractures, treatment with bisphosphonates is well supported by clinical evidence that may underestimate benefits; however, for patients with osteoporosis based on bone density alone, treatment benefits are less certain. ..."

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