@bayhorse I got diarrhea too and sick... my rheumatologist said to drink milk with it and take it at night...i did and that worked for about 9 mos. then i was suffering again from diarrhea so quit taking it last Oct..i feel fine and cannot tell of any difference...each of us are so different...i would not want to be a dr. these days with all the options...but i do think it has a lot to do with the dr. I am wishing you good luck!! Im Irish..so maybe it will help...