@karenschmitt hi Karen I had terrible joint pains afterletrozole prescribed in 2018. My breast cancer was caught early had 15 sessions of radiotherapy. I told my consultant I had no quality ty of life so stopped the drug. I have rheumatoid arthritis according to my rheumatologist be,cause, of the drug!!!!!!! Who knows if I would have got other.wise seems a coincidence. Hope you can make a good decision for you