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Optimal Duration of Hormone Therapy

Prostate Cancer | Last Active: 3 days ago | Replies (40)

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Profile picture for northoftheborder @northoftheborder

Of course, if the prostate cancer doesn't return, you have a 100% chance of dying of something else (some day). 🙂

More seriously, I don't have the patience to watch many videos (someone taking 10 min to say what I could read in 30 sec), but I expect it was discussing attempts to find the point where the line of decreased risk of dying from PCa crosses the line of increased risk of dying from ADT side-effects like heart disease, diabetes, kidney disease, etc.

That crossing point must vary wildly by person and type/severity of cancer. It's one reason we ADT "lifers" get so much extra bloodwork beyond just PSA tests in our 3- or 6-month labs, as well as periodic scans like DEXA, so that they can spot the first early-warning signs of strain on vital organs or bones.

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Replies to "Of course, if the prostate cancer doesn't return, you have a 100% chance of dying of..."

Dear @northoftheborder, you should view this video. It is to the point and well worth your time. It is not discussing attempts to find that intersection. It is 40 well-known oncologists looking at 1000 patients and setting very clear lines for intermediate and high-risk PC. It does NOT talk about metastatic cancer. This is cancer confined to the prostate considering 3 risk factors that modify that timing. It also clearly suggests (although doesn’t explain why) going beyond that increase mortality risk.