@service1010

Your situation sounds similar to mine. AS since 2012 with low psa scores until they rose to 6.2 last year over a six month period. MRI showed One small lesion about 10 millimeter.

Targeted biopsy showed Gleason 8. Elected to have 5 session proton sbrt. Oncologist wanted ADT for 6-18 months. My understanding is that ADT during radiation helps a lot, and not so much after the radiation. I chose to do 5 months of Firmagon. Side effects were minimal other than reducing testosterone to near zero and loss of libido. Firmagon has a half life of about 55 days I think? So I will be “on ADT” for about four more months before Firmagon is mostly gone. Current psa is < .02 or undetectable.

If I had it to do over again, I would do the exact same thing. My opinion is that the two of you should consider short term ADT.

Of course, my kindness and best wishes your way, whatever you decide.