I know that Medicare and/or Blue Cross will not cover IM or IV Ketamine injections. Supposedly, they do cover the esketamine (Spravato). My provider is working on getting insurance approval for Spravato now. Today, I'm having my first IM Ketamine injection for treatment resistent depression. In about a month in Texas, most clinics will not be able to give the injections anymore because the medical board is placing so many restrictions on the clinics it won't be cost effective. They will only be able to give Spravato. I've heard that the IM injections start to work much more quicky and much better. I'll have a series of 6 injections to determine dosage, then would have had a maintenance dose every few months if it were to be available. Now I'll have the 6 injections, then probably start over with Spravato. I'll post how it goes. My daughter has gone to the same clinic and the IM injections have really helped her.