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Has anyone on letrozole experienced extreme fatigue?

Breast Cancer | Last Active: 21 hours ago | Replies (27)

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I took letrozole to reduce the breast tumor (ILC) for 6 months and found I was so fatigued, feeling “down”, etc. I was able to switch to anastrozole which I have now been on for 3 months and I feel much better. I am scheduled for the “Goldilocks Mastectomy on 3/26. Talk to your doctor as there are several different AI’s you could be switched to. Knowing this doesn’t end with surgery but I will be taking this medication 5-10 years. I’m concerned about long-term use but must trust my oncologist surgeon along with my faith. Keep communicating with your doctors to get answers as we know our bodies best.

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Replies to "I took letrozole to reduce the breast tumor (ILC) for 6 months and found I was..."

@buckokey thanks for your insight. I had ILC too but had surgery first. The fatigue seems to just be kicking in. I see my oncologist in May and will ask her about switching. Do you have aching joints too?

@buckokey
I have only been on letraxole for 7 weeks but am exhausted, useless, and stunned! I fall asleep the moment I sit down down( except at night unfortunately ).I try to get out for 30 minute walk each day. It helps a little with my mood which is poor. I have had a dx of fibro since 2013 but I could roll with it and partially ignore it. Now I can barely function. I haven't completed all the necessary surgery -- there have been delasy, wait times and and then discovery of axillary nodes. So I won't try a break from letrazole until all the cancer has been removed. ( "Very " ER positive ). I hope that a break from AI will help clarify what's going on. When you have multiple chronic conditions everything blends into everything else to the point you can't really tell what is going on and what you can do ( if you have any energy to DO anything...) to improve the situation .
Thanks for listening. Nice not to feel alone.