@kasper1 did your Dr have you start each of the 3 meds separately? I did mine one at a time. One the first week, add in the second on week two then the third on week three. This was recommended initially to help determine tolerance for each medication. I agree it’s hard to consider stopping then starting back up however it may help to identify if one medication is the culprit for the issues. Even though I did develop a lot of joint pain during week two, my Dr advised to start up the 3rd medication.