I have been on Kevzara for 1 1/2 yrs. I was able to taper off Prednisone shortly after starting. My CRP & ESR were very high before starting and have remained very low since I have been on it. I do go through periods when I experience pain in my neck, shoulders & lower back. This pain is nothing compared to what I experienced prior to Kevzara. My rheumatologist has determined that I also have Fibromyalgia. My PMR was brought on by Long Covid. It seems like a "gift" that just keeps giving. Good luck!