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Long-term side effects for Gem/Doce ttreatment for NMIBC?
Bladder Cancer | Last Active: 5 hours ago | Replies (32)Comment receiving replies
@mochat hi, I heard due to the unavailability of BCG they are using Gem/Doce. This totally sucks as it's a chemo combo where BCG is not. We were told that would be our treatment. My husband goes to the VA . So the government can't get this non-chemo agent? Ridiculous. Is this what happened in your case. And I agree being injected into the bladder it should not have any systemic effects. Should be the same as HRT suppositories which I am on. I'll try to find some answers for you?
Replies to "@mochat hi, I heard due to the unavailability of BCG they are using Gem/Doce. This totally..."
@dallio
Hi, I did not have any success with BCG so that’s why I was put on GemDoc, once a month for 5 weeks and just had a Blue Light Cystoscopy which showed some inflammation. 2 biopsies were taken and I will hear this week what the results are.
I have just read on another comment that GemDoc can cause inflammation. Also although there should be no usual chemo reactions I have found I am loosing a lot of hair.
I hated the GemDoc treatments but recovered quite quickly from them.
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@dallio hi again I just read it causes severe inflammation of the already irritated bladder wall and due the time of 90-120 minutes of time for each dose it can cause "leaking" through the bladder wall. So in my opinion if the first dose causes severe inflammation the second third and subsequent does a week apart are being injected into an already irritated inflamed bladder. The bladder wall never gets a chance to recover before they giving you another dose. I hope this helps. Hugs