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@harborside24
Thank you for finding this particular post which is the closest thing to a peer-reviewed article I've been able to find to present to my doctor. Thank god Endodoc provided this critical protocol, though I wish we could identify the original trial research citation. I made a copy of this protocol and presented it to my oncology PA who ordered my infusion. In my case it was for Zometa rather than Reclast.
It was unclear to me whether the nurse doing the infusion diluted the Zometa as described. I got the feeling she did not but set me up with what was provided. Because I was not sure about whether it was diluted per this protocol, I requested a saline flush both before and after. I must have read that as a suggestion somewhere and asked for it because I don't know if the nurse would have done that just because I requested it.
My infusion was almost an hour. Lots of hydration, tylenol, etc. My nurse did not give me a tylenol during the infusion, if I recall correctly,, but I did take it on my own. I do not recall any major side effects.
Replies to "@harborside24 Thank you for finding this particular post which is the closest thing to a peer-reviewed..."
@prarysky, the recommendation comes from a single knowledgeable bone expert who devised the method for his own patients, There wasn't formal research, a trial or a formally published citation.
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@prarysky Wonderful! I, too, had the saline before and after the infusion. It is standard practice where I go. Thank you for contacting me. It warms my heart to think that we are all helping each other with this. But I'm angry about the number of docs and infusion centers that don't seem to have a clue how this infusion is to be administered. How many patients are out there who were never told how to prepare or what the infusion process should be? And how many of those patients possibly suffered needlessly? I will never forget my endocrinologist telling me that "infusion centers are not all equal"...boy, was there truth to that!