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What is treatment for Gleason Score 8 at 80 years old in good health?
Prostate Cancer | Last Active: Mar 5 10:46am | Replies (87)Comment receiving replies
@cadaddy Interesting comment about “…early introduction of ADT a month and a half prior to SBRT.”
There have been studies looking into whether it’s preferable to front-load ADT with radiation treatment or backload it. This is a paper titled - “In Prostate Cancer, ADT After RT Better Than Before RT” - that was presented at the American Society for Radiation Oncology (ASTRO) 2020 Annual Meeting —> http://www.medscape.com/viewarticle/940049)
It discusses whether (and why) ADT with (and after) RT leads to better outcomes than ADT well before RT (which is how it is usually given).
It’s always difficult to know which way is best with so much information available.
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For as long as you're on ADT, your PSA should remain undetectable. My medical oncologist compared hormone therapy to training wheels on a bicycle - at some point you have to take them off and see if you can go without them.
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@brianjarvis Since the report is from 2020, I wonder if the use of different radiation therapies - SBRT was less available in 2020 - would have affected the result. My oncologist and RO both strongly urged beginning ADT well before radiation treatment. The idea of weakening or shrinking the pc prior to the radiation was convincing to me.