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PSA spike over a year. Seeking knowledge.

Prostate Cancer | Last Active: Mar 3 10:25am | Replies (20)

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@jim18
Great advice and really helpful. I’ve requested a digital exam, but was told by others that’s not really conclusive.
Should I request the antibiotic? Maybe retest sooner with the free PSA?

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Replies to "@jim18 Great advice and really helpful. I’ve requested a digital exam, but was told by others..."

@asgmiami1 I would skip the DRE. At your PSA level not likely to show anything. Your doctor probably suggested 5-6 months since any infection will probably resolve itself without treatment in that time. If anxious then get the antibiotics (usually a 2-3 week course) and then retest in a month or two. Statistically with first PSA between 3 and 10 the probability of having prostate cancer is about 25%, but many on this board including myself have beat the odds and were positive. My insurance discount cost for the PSA Free test is $11, PSA $11. $22 for both. That will give you another data point. As mentioned, normal prostate cells produce PSA. The test works because cancer cells put out 10-100 times the PSA as normal cells; however, normal prostate cells put out this level of PSA when inflamed by infection or activity.

Unless you want to drop a lot of $$$ skip anything else. PSE is great (about $1K), so is mpMRI on a 3T machine ($1-$2K) neither of which will be covered by your insurance at this point.

If you do have prostate cancer, it is likely to be 3+3 Gleason (low risk) and the recommendation will be to monitor to see if it progresses (i.e., wait for 6 months to a year). Most treatments have a high probability of negative lifestyle impacts (ED & Incontinence) that you probably will want to delay.