Hello @packratfl, were you able to follow up with Mayo Clinic Regenerative Medicine about a stem cell treatment for your knee?

I also have advanced degenerative arthritis with bone on bone in my right knee and the left knee is not a whole lot better but it is functional. The outcome of my recent consult with ortho at Mayo was some PT for ROM stretching, strengthening, and gait training. Then if that doesn't work maybe a steroid or gel shot for the knee. My pain is not bad, probably a 2 or 3 on a scale of 10 but my mobility, balance and walking are impacted and limits pretty much everything I would like to do except watch TV ☺. I've read through the Mayo website information on the stem cell treatments - Bone marrow aspirate concentrate (BMAC) injections and Platelet-rich plasma (PRP) injections.

I had surgery in the mid 70s for torn cartilage in my right knee and it was kind of a botched surgery in that they opened the wrong side of the knee and ended up removing the cartilage from the opposite side. Then in 2007 I had issues with my right leg - gout in the foot, swollen right knee and a diagnosis of polymyalgia rheumatica (PMR). The put me on prednisone and they also aspirated and injected the right knee and it provided relief almost immediately. The PMR has gone into remission but the knee has been bothersome on and off for the past few years. I start my PT today but I'm really doubtful that it is going to do squat for fixing the knee or even making it feel better. I'm kind of looking down the road to see if either stem cell therapy or aspiration of the knee with another shot would be the better option.

Thanks in advance for any suggestions or information.

John