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DiscussionNot Good News after prostate biospy when MRI didn't look too bad
Prostate Cancer | Last Active: 2 hours ago | Replies (140)Comment receiving replies
Replies to "@brianjarvis Yes I posted the PSMA results above and the only place that got a score..."
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@diverjer There are a number of fluids, tissues, and organs that express PSMA without being prostate cancer, and will show “increased radiotracer uptake” in a PSMA PET scan. A person who is well-trained in reading PSMA PET scans will see these and know there’s a low likelihood of it being prostate cancer.
As Dr. Johnson (of Mayo Clinic) mentions in that presentation I sent you previously, an MRI might see all sorts of lesions (like bone and rib lesions), and not be able to tell whether it’s an old healed break, a sclerotic remnant, a fibrous dysplasia, or prostate cancer.
However, if that suspicious rib area is expressing PSMA and shows “increased radiotracer uptake” (of what SUVmax?????), then the likelihood of it being prostate cancer is higher (which is why they concluded that “Osseous metastasis is not entirely excluded. Recommend continued attention on routine oncologic follow up imaging of the rib.”)
If it were me, I would be confused as well and would ask them to further investigate this. After all, if this is a metastasis (and hopefully it’s not), it would totally change treatment management.