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Radiopharmaceutical treatment now instead of last resort.
What if you're 50 and want to give Pluvicto (or similar radiopharmaceutical) a try now? Why wait until using it as a last resort? Let's assume insurance providers would allow us to take the Pluvicto treatment earlier. Should I travel overseas to get the treatment?
P.S.
Radiation is coming in May. Currently on ADT
Age 50
Gleason 10
Stage 4
Local metastasis to glands and lymph node
Orgovyx and Nubeqa for 2 months. PS down to 0.45-ish
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@jeffmarc Just asking as you have a great knowledge base. Is my understanding the Pluvicto does not cure prostate cancer and only knocks it down for months correct?
@chippydoo
In my experience, Listening to a few dozen people that had Pluvicto, The cancer always comes back. I know of some people that went a year or two, It’s more likely to come back within 8 to 10 months it seems.
After writing this, I checked AI and it says 7 to 13 months before it usually comes back. Guess I wasn’t too far off from the actual statistics.
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1 ReactionThanks,
@jim18 you are correct about advantage plans!! When I got Medicare, I got the GAP plan where I have traditional Medicare and insurance for the 20% Medicare doesn't cover. The GAP plan insurance for the 20% is around $50 per month.
I can go to any doctor I choose that takes Medicare without any referral whatsoever. It sure helped with this PC crap I'm dealing with. Never had a question asked.
My corporate medical plan when I was working was pretty damn crappy and it was with one of the largest defense contractors in the world, might even be the same one Lanksta25 was referencing.
Dave
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What is next after Pluvicto besides chemo?
@deltadawn78
Clinical trials. If your ARPI fails and you’ve had Pluvicto and chemo there is no current drug or treatment available. That’s what we’re waiting for, A treatment or a drug that actually works once the current panoply of treatments stops working.
If you have BRCA2 or some other specific genetic issues then a PARP Inhibitor may work.
@jeffmarc And if they’re eligible, there are Immunotherapies/Checkpoint Inhibitor therapies
> pembrolizumab (Keytruda)
> sipuleucel-T (Provenge)
@brianjarvis
Keytruda has really not been shown to be successful with prostate cancer patients. People can try it, but I have not heard of anybody that had success with it.
Proveng Is a useful thing to do, but it is recommended to do the procedure when people’s PSA is very low. If someone is facing the last treatments, their PSA is probably not very low. The actual success of Proveng, in giving someone a long-term overall survival, is not always great. It’s definitely worth getting if you do it early.
Provenge (sipuleucel-T) is a generally successful, FDA-approved immunotherapy for asymptomatic or minimally symptomatic metastatic castration-resistant prostate cancer (mCRPC). Studies show it extends median survival by approximately 4.1 months, reduces the risk of death by 22.5%, and, in real-world data, has shown potential to prolong survival by over 14 months.
Survival Benefit: Clinical trials indicated that 31.7% of patients treated with Provenge were alive after 3 years, compared to 21.7% in the control group.
Optimal Candidates: The treatment is most effective for men with lower PSA levels, as it is designed for earlier stages of advanced disease before significant pain or symptoms develop.