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Serial mpMRI’s

Prostate Cancer | Last Active: Mar 1 2:24pm | Replies (23)

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@handera

For my husband there was no "classical" trend, his PSA went up and down, Free PSA was in normal range, PSA was in normal range, the first genetic test showed "low risk in 30 years". His PSA overall did go up in 15 years of surveillance but there were no jumps , it went up and down and somewhat up which was consistent with the aging and prostate growth in size. The only indicator for a new biopsy was that no biopsy was not done in 7 years, and new small lesion appeared in the left part of a prostate. And yes, second biopsy was not correct , he was not 4+3 but actually 4+5 after his gland was examined post RP.

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Replies to "@handera For my husband there was no "classical" trend, his PSA went up and down, Free..."

@surftohealth88 It seems that every one of us has his own unique prostate cancer ‘signature’. Your husband’s results and years of AS prove that one size does not fit all, and sometimes the trend is NOT your friend - if there is even a trend to be found…so difficult for us to pigeonhole.
And what about a man with a PSA of 1.0 or 1.5 who is found (by some coincidence or miracle) to be totally asymptomatic with a Gleason 10 -discovered on post surgical pathology??
I met such a man at my surgeon’s office; he demanded a biopsy (notwithstanding his urologist’s protests) because he watched his best friend die from PCa and it frightened him into action. He wasn’t letting that happen to him, no matter what.
The anomalies and outliers are so pervasive that we probably need many more grades, categories and subtypes…it’s enough to drive you nuts🤯
Phil