Connect
← Return to Boys, sometimes this gets me down
Discussion
Boys, sometimes this gets me down
Prostate Cancer | Last Active: Mar 5 8:42am | Replies (49)Comment receiving replies
my husband feels exactly like that! a shell of a man! He dreams of the day we can have sex again like normal couples. Maybe he'll get a pause from ADT, maybe not!? Stage 4 metastatic, been on Firmagon and Zytiga for almost a year now and scans showed great improvement after chemo last summer. He's 56 now.
It sucks and gets us both down! I'm actually going to see a therapist tomorrow!
Hang in there!
Replies to "my husband feels exactly like that! a shell of a man! He dreams of the day..."
Connect
@beaquilter Good news for you and your husband: there's starting to be a shift in thinking about stage 4 prostate cancer and ADT.
Up a few months ago, consensus was based on studies like SWOG, which had shown that intermittent ADT had worse outcomes for metastatic prostate cancer, even though it showed promise for earlier stages of the disease.
Now the LIBERTAS study is starting to dive more into the details (instead of treating all advanced prostate cancer as a single group), and preliminary results suggest that intermittent ADT might work for *some* metastatic/stage-4 situations if you keep taking an ARSI (specifically Apalutamide in this study).
There's no long-term data yet, but the latest batch of early LIBERTAS results came out just last month. This is how fast things are moving in prostate-cancer treatment: if your oncologist takes a 4-week vacation, best practices might have changed significantly by the time they get back (!)
https://ascopubs.org/doi/10.1200/JCO.2024.42.4_suppl.TPS236