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Inconsistent diagnosis?

Posted by douglasmayo @douglasmayo, Feb 25 9:09am

I was given a 3 plus 3 diagnosis about 14 months ago. Decipher was middle range. After about 12 months I had another MRI that showed the spot on my prostate grew from 1.3 to 2.1 cm. They decided a PET scan was in order that suggested more extensive cancer that may be in an adjacent lymph node. At the same time the SUV numbers are low and my PSA is at 2.05. The oncologist wants to either: 1) start hormone therapy for 2 months 2) do another biopsy 3) do nothing for three months and do another scan as my numbers are not high and it may not be anything. I am told the PET scan is clear and definitive. Not sure I want to start with Hormone therapy as the side effects appear to be not great. Any suggestions are much appreciated

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jeff Marchi | @jeffmarc | Feb 26 1:39pm
In reply to @mynewlife2026 "Hi Profile: • Age: 56 • PSA: 10.5-->9.9 in 1 month • Prostate volume: 33 cc..." + (show)
Profile picture for mynewlife2026 @mynewlife2026

Hi
Profile:
• Age: 56
• PSA: 10.5-->9.9 in 1 month
• Prostate volume: 33 cc
• isoPSA: 17.7
• MRI: Negative
• DRE: Negative
• Family history: None
• Symptoms: None
Factors lowering risk:
✔ Negative MRI PI-RADS score : 2
✔ Negative DRE
✔ No family history
✔ No symptoms
Factors increasing risk:
⚠ PSA near 10
⚠ PSA density 0.30
⚠ isoPSA 17.7
Am I a candidate for monitored surveillance instead of immediate biopsy?
• What criteria would make surveillance safe?
• What PSA level or change would trigger biopsy?
Given my negative MRI, would a systematic biopsy still likely detect clinically significant cancer?
What are the risks of delaying biopsy in my case?
What are the complication risks of biopsy for me?
What’s my risk of undiagnosed prostate cancer?

I am new to this all these, please guide me through the prudent steps for the future course of action and Suggestions. Thank All in advance.

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@mynewlife2026
Get a PSE test. It will tell you, whether or not you have prostate cancer in your blood stream, it is 94% accurate.

Your PSA density is quite high. MRI is pretty good. You need more information and a PSE test can answer your main question, is there prostate cancer in your system.

An MRI doesn’t always detect PC growth.

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ruralgal76 | @ruralgal76 | Feb 26 3:11pm

After radiation treatment my son now 6 mos later had clots in his urine: going for hyper baric chamber help to get rid of clots… this is so incredibly crazy, he’s scared I’m his Mom 👩 nothing but try I guess

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