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Relationships with our doctors

Pancreatic Cancer | Last Active: Feb 26 11:03am | Replies (6)

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Profile picture for mcharlesfrancis @mcharlesfrancis

As a new patient, I want to share something important. I did develop neuropathy during treatment with Abraxane, and it can be one of the more challenging side effects.

Some patients use cold therapy (icing hands and feet during infusion). Cooling may restrict blood flow to the extremities, which can reduce the amount of chemotherapy reaching the peripheral nerves and may help lower the risk or severity of neuropathy.

It’s not a guarantee, and it’s important to discuss it with your oncology team first, but if I were starting again, I would seriously consider using cold therapy from the beginning.

Neuropathy is much easier to try to prevent than to reverse.

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Replies to "As a new patient, I want to share something important. I did develop neuropathy during treatment..."

@mcharlesfrancis That is really good advice. Often patients do not realize what neuropathy can do. Great recommendation and makes total sense.

@mcharlesfrancis
Thank you for your kind words.

When I went back on chemo after my Whipple, I asked for capecitabine because in 2016 there was news that it had been very successful in a trial in Europe. Be careful what you wish for! I gave up capecitabine in about two weeks because I could barely walk due to the neuropathy. I continued with gemcitabine alone for about 6 months. I tolerated abraxane very well, and my 4 months of neoadjuvant chemo with gemcitabine and abraxane brought my CA 19-9 down from about 1300 to 20.