@pesquallie
The three months shot completely leaves your body within a few days of three months. The half-life of Lupron is 3 hours, so it is quickly out of your body.

If you are referring to the fact that your testosterone doesn’t come back right away that is accurate but as the stampede trial showed having testosterone over 50 is a problem. For most people, it won’t come back that quick, But you never know.

People who have aggressive prostate cancer need to keep their testosterone quite low all the time, Or at least until they become castrate resistant, and in that case, maybe a high dose of testosterone actually might help.

I keep a record of every single PSA blood test. I had my 6 month Lupron shot late by three weeks one time. Instead Of my PSA being undetectable this was the reading after I was three weeks late

PSA 0.6 11-14-17 lupron shot late

The next month, my PSA went back down to undetectable. So yes, not getting the shot on time can make a major difference in your PSA.