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Anyone experience pain with Y90 treatment?

Cancer | Last Active: 2 days ago | Replies (39)

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Profile picture for allmyfriends @allmyfriends

@marthawyatt Would love a follow up. Y90 on 1/14/2026 for cancer that spread from esophagus to the liver and after two weeks same type of concerns. Difficulty swallowing, lost 30 pounds in three weeks, unable to keep food or water down, not able to sleep for more than a couple of hours.

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Replies to "@marthawyatt Would love a follow up. Y90 on 1/14/2026 for cancer that spread from esophagus to..."

@allmyfriends
I am sorry to hear about what you are experiencing. I am fortunate enough to have a neighbor who is a retired GI doctor. He got me in with a new GI group, and within 2 weeks I had an endoscopy where they found 2 ulcers, one worse than the other. They biopsied the larger one and found remnants of a radioactive bead.

I have lost 20 pounds. I am treating the ulcers with liquid sucralfate and a prescription for Prilosec. I had the endoscopy on Jan. 28, and the medicine eased the pain within days; however, I am still building up my diet, and I still fill up after, say, a whole sweet potato.

I can't take my oral cancer meds because they irritate the ulcers. I am starting chemo next week, which scares me; I had my first chemo in 2019. Feels like I am starting over again.

There is a syndrome associated with the Y90 you have probably read about, with extended recovery. I found a few other stories on the Mayo site. I never had nausea, just extreme pain in my abdomen.

Has the interventional radiologist given you anything for nausea? Talk to them about the syndrome and maybe some painkillers as well.

Sorry for the long-winded response. Please let me know how you make out.

I teach college and had to find people to take my classes this semester.