@michieg first of all, congratulations on your truly phenomenal results. What a relief for you!

We’re all so different, and that’s part of why treating diseases like osteoporosis is so complicated. I would not take any form of estrogen because my mother died quite young of breast cancer that she developed in her mid-thirties (I know there’s new thinking on this) and because while taking raloxifene to support my bones after my hysterectomy I developed a massive blood clot behind my knee that led to three additional clots in my calf, along with major pain and lots of anxiety. The combination of these two factors, for better or for worse, makes me very nervous about hormonal treatments.

You are right about the need to transition after Tymlos, although my endocrinologist, who specializes in bone and metabolic disorders, said that I’d be ok for up to three months without a new med (it will not be anywhere near that long). She does not recommend Reclast, and, perhaps because I’m old enough that time limits for Prolia seem fanciful, thinks that’s the best route.

Best of luck to you. Your results were truly stratospherically good.