I have Sjogren's Disease and Lupus and I started HCQ last April 12th 2025 and after approximately 2 and 1/2 months I noticed a lessening of pain from Sjogren's Disease. However, as time went by I noticed that I was becoming very anxious. On September 14th 2025 the anxiety was so severe that I stopped taking HCQ. This medication has a long half life when it is in your body so it can take up to 50 to 60 days for it to completely leave your body. Somewhere between 50 to 60 days the anxiety started to fade. This was probably the worse experience in my life as I couldn't be alone because of sheer terror. I felt as though I had an psychotic episode and would never be the same person as I previously was. I saw an extremely experienced acupuncturist who helped, I practiced acupressure, I sat on my elliptical for one hour a day, I took one drop of a mild marijuana tincture and slowly I returned. That was a nightmare. I have a corneal specialist that I see at Mass. Eye and Ear Boston and she told me that only one of her patients actually became totally blind after taking it for an exceedingly short time ?3 to 4 months perhaps. Hope this information helps you.