botox worked great for my gastroparesis. I had it down to the lower sphincter in the stomach and that way, when the food gets there, a hole is always open allowing it to enter the small intestine. Botox is injected into 3 small areas of the muscle. With stomach contracting so slow, by the time the food reaches the bottom, the muscle is closed. Food can collect and "rot" causing infection. Botox keeps the muscle slightly open allowing food to exit in small amounts preventing this. I had it done January 2014. The daily nausea and vomiting are gone and excessive weight loss. I still have limited foods I can eat but NO pacemaker. Botox is still working and is a blessing. I use liquid erythromycin (granules) to make my stomach contract and eat small meals. My vitamins are gummies or chewables and foods must be easily digestible. Breads have to be white (refined) nothing that takes long to digest causing further problems. A wonderful dietician helped me. I am not diabetic and it was caused by medications. As an RN, I never had encountered it. My case was/is severe. The botox really saved me. Best of luck! Joan