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@handera A PSA Density threshold of 0.15 (sometimes 0.20) or above is commonly used to trigger further investigation. Yours is borderline.
Regarding the MRI results —> October 2023 (3 lesions; PIRADS 3/4/5), October 2024 (1 lesion), and February 2026 (1 lesion; PIRADS 4). Have you had definitive confirmation on the status of those lesions?
With the changing number of lesions seen, have you obtained second opinions on those? A PIRADS score is a specialist’s educated and expert “opinion” of what he (or she) believes they see in an image - it’s often as much an art as it is a science. It’s always valuable to get 2nd opinions - especially with lesions disappearing. (Lesions don’t simply “disappear.”)
And the % Free PSA also provides valuable information as to what steps to do next.
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@brianjarvis
Started with a new urologist last November, next appointment tomorrow, will see what he has to say about latest results. He was quite comfortable with my continuing AS, based on numbers and condition before latest results…which have just improved in the meantime.
I will not have another biopsy, due to suffering from Dysorgasmia for months after previous biopsy (lingering effects even 2.5 years later….I know, I know it’s rare….but personal experience trumps pablum medical SOC answers and the higher likelihood (in my case) for another Dysorgasmia reoccurrence in any subsequent biopsy, based on proven research.
I will be asking for the My Prostate Score 2.0 test (or possibly the PSE test)…it will be my only option to a biopsy….of course I’ll continue regular PSA and mpMRI’s….but no more biopsies…
I would be willing to submit to some form of advanced radiation therapy, if/when there is clear evidence of significant progression….but another biopsy is out of the question….therefore a second opinion, in my particular case, is moot.
BTW: Research indicates that MRI “lesions” often disappear for those diagnosed with low risk prostate cancer…it’s because they were originally only inflammation areas, which were misidentified as cancerous “lesions” in previous mpMRI’s…that’s what happened in my case…check out the research…