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My current prostate volume is 44.6ml. My current PSA result of 6.47 PSA indicates a PSA density of 0.145.
At my October 2023 diagnosis, my prostate volume was 43.5ml with a 7.8 PSA indicating a PSA density of 0.179.
My original Oct 2023 mpMRI found three lesions: one PIRAD 5 (2.2 x 1.1 cm), one PIRAD 4 (0.7 cm) and one PIRAD 3 (0.9 cm).
An Oct 2024 follow-up mpMRI found only one lesion (now 1.9 x 1.1 cm), while the other two were not visible.
My latest (Feb 20, 2026) mpMRI also only found one lesion, now rated PIRADS 4 and 1.1 x 0.4 cm.
My 12.3 year PSA doubling time, PSA density reduction from 0.179 to 0.145 and serial mpMRI lesion size reductions are all favorable for continuation of my active surveillance protocol.
Replies to "@brianjarvis My current prostate volume is 44.6ml. My current PSA result of 6.47 PSA indicates a..."
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@handera A PSA Density threshold of 0.15 (sometimes 0.20) or above is commonly used to trigger further investigation. Yours is borderline.
Regarding the MRI results —> October 2023 (3 lesions; PIRADS 3/4/5), October 2024 (1 lesion), and February 2026 (1 lesion; PIRADS 4). Have you had definitive confirmation on the status of those lesions?
With the changing number of lesions seen, have you obtained second opinions on those? A PIRADS score is a specialist’s educated and expert “opinion” of what he (or she) believes they see in an image - it’s often as much an art as it is a science. It’s always valuable to get 2nd opinions - especially with lesions disappearing. (Lesions don’t simply “disappear.”)
And the % Free PSA also provides valuable information as to what steps to do next.