Getting ready to take my first dose of Orgovyx and Abiterone.....

Posted by stage4lovolmetpc @stage4lovolmetpc, Feb 20 1:52pm

I have had the drugs in my hand for 2 days now and am hoping to be able to start them this weekend. I am having a hard time saying goodbye to my old life and starting my new one. For background, I am 72, went to the ICU in Aug 2025 with a huge blood clot in my arm. 3 days later left with Eliquis and a PSA of 66. Had a digital exam, hard lump. Dr did biopsy Sept 2025. 14 out of 14 cores positive, Gleason 8 4+4. Dr said the clot was caused by the cancer.
Psma petscan with Posluma Oct 2025. Stage 4 low volume met pc.
Monthly PSA went from 66 to 58 to 50 now its at 55. Testosterone was 290, 330, 338 now 430. After bargaining with myself and the Dr, Feb 2026 the nurse supervisor came in and had a talk with me...bone cancer is not pretty. So I am resigned to the fact that I have to do this, to slow the spread, shrink the tumor that my prostate has become and be responsible for my health going forward. Doing nothing is no longer an option. I have been reading the posts here for weeks, doing my research and going back and forth on what I will do....and now the time has come....800 dollars worth of one months drugs are waiting for me....I hope I can take them soon...laughing at myself....still bargaining.....maybe just one more day....

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

I was diagnosed at age 69 with a Gleason score of 8 right mid lateral and 7 right mid. I'm surprised radiation treatment has not been included. I received 6 weeks of daily radiation sessions and it destroyed the cancer. The side effects consisted of periodic fatique, gastrointestinal issues and some weakness. I was also prescribed Orgovyx and Aberaterone. Total time for the hormone therapy is 2 years.
I've had some struggles with the side effects (shrinking testicles with some discomfort, inconsistent bowels, irritability and some depression). All mentioned managable. The psychological piece has been more difficult for me. Loosing testosterone production is not easy on our bodies. The loss of labido has been hard for me to overcome. I have a very loving and understanding wife. She's been solid in her support for me.
I'm not letting this cancer and treatment take me down. After 8 month's of therapy I have slowly found ways of empowerment. I exercise even when I'm not feeling it. I still make love to my wife. The drive is not there, but the intimacy is. I stay active (pretty good cornhole player) but I do make sure I have plenty of downtime. My attitude and overall outlook on life has improved.
Your experience with side effects may be different. Regardless, find ways where you can participate in your healing. Be empowered!

REPLY

Good morning folks. First, I would like to thank each and everyone of you for taking time to comment on my post of several days ago. Second, I would like to tell you that I took the loading dose of Orgovyx Sunday evening and the first Zytiga pills at 4 am this morning. I had a great weekend and while sitting out by the bonfire on a beautiful winter evening last night, dogs on either side of me, I thought: life is pretty good. I will keep you informed and will continue reading all the post here, this really is a good resource for PCa patients, and it reminds me that we all have our trials and tribulations. I hope I can rise to the level of grace and dignity of some of you have shown. So, one step forward, in what, I am sure, will be an interesting trip...laughing to/at myself: "what a long strange trip it has been" Waxing poetic on a Monday morning? I am already embracing my new reality! Thanks again, it was just the push I needed.

REPLY
Profile picture for stage4lovolmetpc @stage4lovolmetpc

Good morning folks. First, I would like to thank each and everyone of you for taking time to comment on my post of several days ago. Second, I would like to tell you that I took the loading dose of Orgovyx Sunday evening and the first Zytiga pills at 4 am this morning. I had a great weekend and while sitting out by the bonfire on a beautiful winter evening last night, dogs on either side of me, I thought: life is pretty good. I will keep you informed and will continue reading all the post here, this really is a good resource for PCa patients, and it reminds me that we all have our trials and tribulations. I hope I can rise to the level of grace and dignity of some of you have shown. So, one step forward, in what, I am sure, will be an interesting trip...laughing to/at myself: "what a long strange trip it has been" Waxing poetic on a Monday morning? I am already embracing my new reality! Thanks again, it was just the push I needed.

Jump to this post

@stage4lovolmetpc
Good for you. As I said above, best wishes.

BTW...love the Dead reference.

REPLY

Well, here I am, 10 days into ADT....and I will have to say that I dont have any debilitating side effects so far.
Tired? Yes, I work hard all day. Hot flashes? Yes, the woodstove is cranking.
Mood swings? No more than usual...lol.
Heres what I have noticed: that pesky 4am morning wood that woke me everyday for the past 60 years has
taken a vacation.... Im not thinking about sex every minute of my life anymore...Ill have to say it is a relief to not have that on my mind all the time...I might have had a problem.... My Father always said he should have had me neutered before I turned 18....you were right Dad! But that aside, it feels good, mentally, that I am doing something proactive to stop that black spider from growing inside me. PSA and T tests at the end of March will tell the story. I have been coming here to read comments and advice everyday, all helpful and educational no matter the author. I will have to make more treatment decisions in the future, so thank you all for the time you take to engage in the sometimes lively posts...laughing again, some of you are very funny....yes, you know who you are: "eunuch calm", Im feeling it! So, lifting weights, walking the dogs, shoveling whatever needs to be shoveled, taking care of business....everything is good here in the woods and its time to get busy.....I hope you all have a good day

REPLY

It’s great to hear you are not having serious problems with ADT. I personally never had fatigue, Even while on a Zytiga, which lowers your testosterone even more. I’ve also never had any of the mood swings some people have, They are not guaranteed. Of course, just having PC can give you mood swings.

If the hot flashes get annoying, come back and tell us we can help. I lived with terrible hot flashes for a year. I would get at least eight every day and I would feel fatigue first and then the sweat would start dripping down into my eyes. My chest would get all wet and under my arms. My oncologist had me get a depo-provera Shot and that stopped it almost completely. There are a bunch of drugs that can greatly cut back on the hot flashes.

Yes, there is one “benefit “ Of ADT. I know I was horny all the time even in my 60s, Now it’s in the past, though if I see an attractive woman, I do still think about it. One of the doctors at one of the meetings I go to commented on this, He said his treatments were much easier to do, since he no longer thought about sex constantly. Definitely beneficial for his marriage.

REPLY
Profile picture for mjp0512 @mjp0512

@stage4lovolmetpc
Good for you. As I said above, best wishes.

BTW...love the Dead reference.

Jump to this post

@mjp0512
Same! I went to about 20 Dead shows in my life. The BEST! 🙂 RIP to Bobby, Jerry, Phil and Brent.

REPLY
Profile picture for stage4lovolmetpc @stage4lovolmetpc

Well, here I am, 10 days into ADT....and I will have to say that I dont have any debilitating side effects so far.
Tired? Yes, I work hard all day. Hot flashes? Yes, the woodstove is cranking.
Mood swings? No more than usual...lol.
Heres what I have noticed: that pesky 4am morning wood that woke me everyday for the past 60 years has
taken a vacation.... Im not thinking about sex every minute of my life anymore...Ill have to say it is a relief to not have that on my mind all the time...I might have had a problem.... My Father always said he should have had me neutered before I turned 18....you were right Dad! But that aside, it feels good, mentally, that I am doing something proactive to stop that black spider from growing inside me. PSA and T tests at the end of March will tell the story. I have been coming here to read comments and advice everyday, all helpful and educational no matter the author. I will have to make more treatment decisions in the future, so thank you all for the time you take to engage in the sometimes lively posts...laughing again, some of you are very funny....yes, you know who you are: "eunuch calm", Im feeling it! So, lifting weights, walking the dogs, shoveling whatever needs to be shoveled, taking care of business....everything is good here in the woods and its time to get busy.....I hope you all have a good day

Jump to this post

@stage4lovolmetpc

That's awesome to hear. I've been on Eligard for 18 months. Things I've noticed are sleep issues, a bit tired at times and of course the manapause. I will say stay ACTIVE as much as possible and do weight training to keep your muscles active. Good luck on your first PSA/T results!!

REPLY
Please sign in or register to post a reply.