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← Return to My PSA climbed 02, .04, .07 .15 .21 had a RP 2 yrs ago PSMA negative ?
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My PSA climbed 02, .04, .07 .15 .21 had a RP 2 yrs ago PSMA negative ?
Prostate Cancer | Last Active: Feb 24 9:59am | Replies (45)Comment receiving replies
@heavyphil Thanks for your comments. Originally my Gleason score was 3+ 4.
I’m the patient who mention PSA climbed slowly and realize the numbers are low.
.02 .04 .07 .15 .21 then then back a fraction to .18
Trying to understand the numbers and what is Happening.. thus went to surgeon who performed RP robotically 2 years ago
He saw my #’s creep up
and asked me to visit his modality clinic.
Instead went to my RO for consultation and compared 2 pathology reports almost 2 yrs apart.
2nd report from PMSA was thoroughly discused
and like 2 yrs ago the RO was in favor of active surveillance and wait and see next PSA in 90 days for another follow up
Appreciate everyone that chimed in and it’s concerning but not alarming. Please comment
How do you feel about my experience, many thanks !
Met with RO
Replies to "@heavyphil Thanks for your comments. Originally my Gleason score was 3+ 4. I’m the patient who..."
@charlotte1216 I have a similar experience. RP in 2020. About 2.5 years later, PSA went from .1 to .28, .38, .42, and .78. The last 3 PSAs within about 3 months. My Gleason was 4+3, and at the time of RP, the cancer had spread to the bladder neck. When my PSA began to rise, they did a PSMA PET scan at .42 and found it had spread to the lymph nodes. I was told I was very lucky that it showed on the PSMA PET scan at PSA .42. Here is one study from URO Today - albeit from 2022.
Key Findings for PSMA PET Detection Rates:
PSA < 0.5 ng/ml: Studies show a detection rate of roughly 38%–42%.
PSA 0.5 – 0.99 ng/ml: Detection rates increase to 57%.
PSA 1.0 – 1.99 ng/ml: Detection rates jump to 84%.
PSA >2.0 ng/ml: Detection rates are very high, up to 86%–97%.
My point is that I would imagine they would repeat the PSMA PET scan if the PSA levels increase. My case now. After ADT, my PSA levels have begun to rise again, from .04 to .07 over the last 3 months. However, they won't repeat a PSMA PET scan until it reaches a much higher level. Wishing you the best.
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@charlotte1216 I cannot comment on what your RO has planned; he’s an expert at this while I am like you: trying to understand.
But I don’t think a second PSMA will show anything; that has been demonstrated over and over. The PSA values are simply too low. You can wait, if you like, until they reach 2 or 3 snd that may show something; that’s up to you.
Your PSA results really DO tell the true story: something is producing PSA and unless your surgeon can tell you that he left a large area of ‘normal’ prostatic tissue behind in order to nerve spare, that PSA is being produced by malignant cells.
That fallback in PSA from 0.21 to 0.18 is common; mine did the same thing. It will probably go up again in 3 mos.
Phil