← Return to PMR and possible GCA - unable to take oral steroids - alternatives?

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Actemra (tocilizumab) works well for me. Actemra is available as a monthly infusion which I have done for the last 3-4 years. I originally got off Prednisone doing weekly injections of Actemra but I switched to a monthly infusion at least 3 years ago.

I was diagnosed with PMR almost 20 years ago and I took Prednisone for 12 years before Actemra was tried, My rheumatologist had to get authorization to give me Actemra to treat PMR. There were some questions about "possible GCA" but my rheumatolgist didn't make the case that I had GCA. I doubt GCA would have ever developed because I needed so much Prednisone for a very long time,

The request to treat me with Actemra was approved with the stipulation that my rheumatologist treat me with Actemra "as if" he was treating GCA.
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By the way ... GCA isn't the only autoimmune condition that can cause blindness, I had a long history of recurrent uveitis which can also cause blindness, I had frequent visits with an ophthalmologist because of more than 30 flares of uveitis ... I lost count at 30. My ophthalmologist would often reassure me that he didn't see any evidence of GCA.
https://www.mayoclinic.org/diseases-conditions/uveitis/symptoms-causes/syc-20378734
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Typical giant cell arteritis symptoms include headache, scalp tenderness, jaw claudication, and polymyalgia rheumatica. Ischemia induced by the arteritis can lead to blindness.

With uveitis my entire eye was being attacked by my immune system and was inflamed.

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Replies to "Actemra (tocilizumab) works well for me. Actemra is available as a monthly infusion which I have..."

@dadcue
Thank you for sharing your history. It’s reassuring to hear that it’s manage. My wife has an appt. This week with her rheumatologist and we will discuss this info.
My wife did not take the methotrexate as she read it really wasn’t helpful for PMR or GCA
She will tell her doctor this week.
The PMR symptoms have subsided
With the one injection of triamcinolone acetonide that the MD gave on Feb. 4th. Because she can’t take the prednisone by mouth and she was miserable with pain, but MD prescribed methotrexate
Has anyone spoke to you about methotrexate being useful?
she thinks she feels subtle signs of GCA, so she will ask for a scan or whatever test to check for that.
My wife is wondering if it’s possible that she had this one time debilitating flare of PMR and maybe never again. One could hope.
You’re very kind to take the time to share your information
I’m feeling good that it can be managed and I hope wife will get the treatment and testing needed for the GCA.
Thank you again